Moleküler Biyoloji ve Genetik (YL) (Tezli) (İngilizce)
Ders İçerikleri
1. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| IGE5500 | Scientific Research Methods and Ethics | 3+0+ | 9 | Compulsory |
| 1. Introduction to Research Methods - Overview of scientific research and its importance - Types of research: qualitative, quantitative, and mixed methods 2. Critical Literature Review - Techniques for conducting systematic and critical reviews - Identifying research gaps and formulating research questions 3. Research Philosophy and Paradigms - Understanding positivism, interpretivism, and other paradigms - Aligning research design with philosophical foundations 4. Research Design and Methodology - Developing coherent research frameworks - Selecting appropriate methodologies for research objectives 5. Ethics in Research - Ethical considerations in research design and execution - Gaining access to data and maintaining confidentiality 6. Data Collection Techniques - Sampling strategies: probability and non-probability - Primary data collection: interviews, questionnaires, and diaries - Secondary data evaluation and analysis 7. Data Analysis Methods - Quantitative analysis: statistical tools and techniques - Qualitative analysis: thematic, narrative, and content analysis 8. Writing and Presenting Research - Structuring academic and consultancy reports - Effective presentation techniques for research findings 9. Practical Applications and Case Studies - Hands-on exercises in designing and conducting research - Real-world examples of ethical dilemmas and solutions 10. Final Project - Development of a mini research proposal - Peer presentations and constructive feedback sessions | ||||
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| MBG5101 | Molecular Biology Methods and Applications | 3+0+0 | 10 | Compulsory |
| During this course, the deeper discussion will be done through a set of conversations related to molecular biology technqiues and recent papers in any field of molecular biology and genetics. | ||||
2. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| IGE5001 | Basic Statistics | 2+2+ | 8 | Compulsory |
| It includes teaching the understanding of basic concepts related to statistics, distinguishing data types, organizing data, and applying basic descriptive statistics and some parametric tests. | ||||
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| MBG5104 | Seminar | 0+0+0 | 8 | Compulsory |
| This course will inform the students on nanomedicine and nanomaterials. artificial tissue engineering, tissue processing, cancer studies. bioinformatics applications, secondary metabolites, in vitro propagation and conservation techniques, engineering applications in medicine and will introduce various types of instrumental analysis. | ||||
3. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| MBG5189 | Thesis I | 0+0+0 | 30 | Compulsory |
4. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| MBG5190 | Thesis II | 0+0+0 | 30 | Compulsory |
Department/Programme Elective Courses
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5000 | Regulation of Gene Expression | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5001 | Current Issues in Molecular Biology and Genetics | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5002 | Plant Genetic Engineering and Applications | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5003 | Molecular Markers in Plant Breeding | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5004 | Epigenetics | 2+0+0 | 6 |
| This course covers all cellular events regulated by epigenetic mechanisms in prokaryotic and eukaryotic cells. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5005 | Genetic, Genomic and Evolution | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5006 | Non-coding Genome | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5007 | Cancer Biology and Genetics | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5008 | Reproductive Biology | 3+0+0 | 6 |
| This course approaches the fundamental structure-function relationships in histology and reproductive biology through an integrated perspective. It begins with the examination of basic tissue types, including epithelial, connective, muscular, and nervous tissues. Subsequently, the histological structures of organ systems are explored in detail, emphasizing the relationship between cellular and tissue organization and physiological functions. The section focusing on the reproductive system covers the microscopic anatomy of male and female reproductive organs, the processes of gametogenesis (spermatogenesis and oogenesis), fertilization, and early embryonic development. Additionally, the potential roles of cellular therapeutic approaches such as stem cells, mitochondria, and exosomes in fertilization are examined and discussed in the context of current scientific literature. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5009 | Omic Technologies | 3+0+0 | 6 |
| This course includes the definition of systems biology and omics technologies, analysis of omics data types, integration of omics data into drug repositioning and molecular pathway analyses over omics data. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5010 | Frontiers in Nanomedicine | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5011 | In Vitro Plant Propagation | 2+0+ | 6 |
| This course focuses on the basic concepts of plant propagation and plant tissue culture, describes in detail sterilization methods and sterile working conditions, as well as plant tissue culture methods and applications. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5012 | Microbial Genetic | 2+0+ | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5013 | Therapeutic Polymer Engineering: Innovations in Healthcare | 2+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5014 | Bioinformatic Applications in Nutrigenetics | 3+0+0 | 6 |
| Course Code | Course Name | (T+A+L) | ECTS |
| MBG5015 | Advanced Genetic Engineering and Biotechnology | 3+0+ | 6 |
| This course is structured to provide a progressive and comprehensive understanding of genetic engineering and biotechnology. It begins with an introduction to recombinant DNA technology and gene engineering, focusing on genome structure, gene expression, and protein folding. Students then explore synthetic gene design, including the use of biological databases and computational tools. The course continues with the isolation and analysis of DNA, RNA, and proteins, followed by gene manipulation techniques such as cloning and mutagenesis and the construction of recombinant DNA molecules. Recombinant gene expression is covered through the study of transient and stable expression vectors, along with an overview of non-viral and viral gene transfer methods. A midterm examination is conducted to assess foundational knowledge. In the latter part of the course, emphasis shifts to biotechnology applications, including enzyme production, antibody production, and the development of transgenic animals. Advanced therapeutic applications are also examined, such as cellular therapies, CRISPR-based gene editing technologies, and CAR-T cell therapy. The course concludes with a comprehensive general review to reinforce key concepts and prepare students for final assessments. | |||