---

Department/Programme Elective Courses

Course Code	Course Name	(T+A+L)	ECTS
MONK6004	Cancer Biochemistry	3+0+0	8
Biochemical markers of cancer, biochemical changes occurring in the process of cancerization, the relationship of metabolic processes with cancer.

Course Code	Course Name	(T+A+L)	ECTS
MONK6005	Omix Technologies in Molecular Oncology	3+0+0	8
Structural and functional research using Genome, Transcriptome, Proteome, Metabolome, Metagenome and Biomarker Concepts and OMIKS Technologies.

Course Code	Course Name	(T+A+L)	ECTS
MONK6006	Tumor Microenvironment	3+0+0	8
Tumor microenvironment cells and components, tumor microenvironment molecular targets and clinical uses

Course Code	Course Name	(T+A+L)	ECTS
MONK6007	Cancer Stem Cell Biology	3+0+0	8
Cancer stem cell hypothesis, hallmarks of cancer stem cells, signaling pathways, drug resistance, treatment approach, clinical significance

Course Code	Course Name	(T+A+L)	ECTS
MONK6008	Cell Death and Cancer	2+2+0	8

Course Code	Course Name	(T+A+L)	ECTS
MONK6011	Trace Elements and Minerals in Cancer	3+0+0	8
Atomic theories, Basic principles of living structures, Physical properties of chemical bonds and bond energetics; Properties determining the structural and functional properties of biomolecules; DNA repair mechanisms and cancer; Chemical and physical structure of water molecule, Role of water in organism, Properties of body fluids, Intracellular electrical environment, Aqueous solutions, Buffer systems; Energy flow in living things; Laws of bioenergetics and thermodynamics; Thermodynamic-bioenergetic concepts in cancer, Cancer and cachexia; Cell injury and adaptation in cancer; Cell death, apoptosis, necrosis; Acute and chronic inflammation; cytokines; Free oxygen radicals and the damage they cause; Oxidative damage mechanisms; Antioxidants and their biological importance; Cancer and angiogenesis; cancer and immunity; Biological importance of trace elements and minerals; Biological importance of iron and copper elements and their importance in cancer process; Biological importance of chromium, cobalt and manganese elements and their importance in cancer process; Biological importance of zinc, selenium and boron and their importance in cancer process; Biological importance of mercury, lead, cadmium and aluminum elements and their importance in cancer process; Biological importance of silicon, nickel and arsenic elements and their importance in cancer process; Biological importance of minerals of calcium, phosphorus and magnesium minerals and their importance in cancer process; Biological importance of iodine, sodium, chlorine, potassium and sulfur minerals and their importance in cancer process

Course Code	Course Name	(T+A+L)	ECTS
MONK6012	Cell death and detection methods	3+0+0	8

Course Code	Course Name	(T+A+L)	ECTS
MONK6013	Metabolic Targets in Cancer	3+0+0	8

Course Code	Course Name	(T+A+L)	ECTS
MONK6014	Bioinformatics and Artificial Intelligence in Cancer 2	3+0+0	8
Oncological data and artificial intelligence modeling constructs will be explained.

Course Code	Course Name	(T+A+L)	ECTS
MONK6105	Cancer Epidemiology	2+0+0	8
Discussing the situation of cancer in the world and in our country. Understanding environmental and facilitating factors in cancer formation. Discussing the role of the immune system in cancer and learning about hematopoietic stem cell transplantation, which is a form of treatment.

Course Code	Course Name	(T+A+L)	ECTS
MONK6112	Bioinformatics and Artificial Intelligence in Cancer 1	2+1+0	8
The content of this course is the effective use of bioinformatics and artifical intelligence tools to understand more about cancer research and molecular applications in the field of oncology. Another important content of the course is to convey basic information about the effective use of existing mathematical models during the experimental design phase and the interpretation of the results. To achieve this goal, the basis of many bioinformatics tools together with artificial intelligence tools is considered as main content of this course.

Course Code	Course Name	(T+A+L)	ECTS
MONK6115	Scientific Research Methods and Ethics	3+0+0	8
Scientific Research Designs Hypothesising Keeping Scientific Records Presentation of Data Scientific Report Writing Academic Publishing and Indexing Publication Ethics

Course Code	Course Name	(T+A+L)	ECTS
MONK6205	Tumor Immunology	2+0+0	8
Basic biological concepts in tumor immunology; cellular and humoral immune response against tumors; cells in the tumor microenvironment and their effects; tumor antigens, immune surveillance and immune editing of tumor; escape mechanisms of the tumor from the immune system; angiogenesis, adhesion molecules and apoptosis mechanisms; immunotherapies as well as targeted therapies in cancer.

Course Code	Course Name	(T+A+L)	ECTS
MONK6206	Experimental Animal Models in Cancer Research	3+0+0	8
Selection of experimental animals in oncological studies, ethics of experimental animals, tumor models, metastasis models and drug applications in experimental animals.