Tibbi Biyoloji ve Genetik (DR)
Ders İçerikleri
1. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6113 | Advanced Cell Biology and the Genome | 2+0+ | 6 | Compulsory |
| As a result of the genome and molecular structure course, students gain knowledge about the structure and functions of the genome after receiving basic information about the cell. | ||||
2. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6104 | Molecular Basis of Diseases | 2+0+0 | 6 | Compulsory |
| In this course, students acquire basic knowledge about the molecular pathogenesis of diseases. | ||||
3. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6107 | Mutation and Mutation Screening Methods | 2+0+0 | 6 | Compulsory |
| Changes in chromosome structure and number, mutagenic effect of these changes (chromosome mutations). What is a gene mutation? Examining the molecular level of gene mutations, types, causes. Spontaneous mutations; Errors that occur during the replication of DNA, spontaneous chemical changes. What is a mutagen? Mutagen types; physical mutagens, types of ionizing radiation and chemical mutagens. Types of damage caused by mutagens in the DNA molecule. DNA repair mechanisms. Different mutation detection methods. | ||||
4. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6171 | Seminar | 1+0+0 | 10 | Compulsory |
| It includes scientific presentations prepared by the student. | ||||
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6206 | Proficiency Exam Preparation Class | 4+0+ | 20 | Compulsory |
| It includes the student's intensive study process in preparation for the proficiency exam. | ||||
5. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6115 | Thesis Study I | 5+0+ | 30 | Compulsory |
| Thesis study | ||||
6. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6116 | Thesis Study II | 5+0+ | 30 | Compulsory |
| Thesis study | ||||
7. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6117 | Thesis Study III | 5+0+ | 30 | Compulsory |
8. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6118 | Thesis Study IV | 5+0+ | 30 | Compulsory |
| Thesis study | ||||
Department/Programme Elective Courses
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6001 | Cytogenetics and Molecular Genetics Techniques and Application Areas | 3+0+0 | 8 |
| The aim of this course is to provide information about cancer cytogenetics and its clinical relevance. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6004 | Microorganism Genetics | 3+0+0 | 8 |
| The nature of microbial nucleic acids and their amplification; molecular hybridization for microbial identification; molecular typing; new technologies; omics in microorganisms; molecular detection of microorganisms; systems microbiology; the pathogen/host interface; antibiotic resistance mechanisms; clinical application of microbial genetics; biotechnological application of microbial genetics | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6006 | Karyotype Writing Rules | 3+0+0 | 8 |
| CHROMATIN CHROMOSOME STRUCTURE, INTRODUCTION TO CHROMOSOMAL DISEASES, PHENOTYPIC AND GENETIC FEATURES OF NUMERICAL AUTOSOMAL CHROMOSOME ANOMALIES, PHENOTYPIC AND GENETIC FEATURES OF STRUCTURAL AUTOSOMAL CHROMOSOME ANOMALIES, PHENOTYPIC AND GENETIC FEATURES OF SEX CHROMOSOME ANOMALIES, OBTAINING CHROMOSOMES, RECOGNITION OF CHROMOSOMES, RECOGNITION OF CHROMOSOME ANOMALIES, REPORTING OF NUMERICAL CHROMOSOME ANOMALIES, REPORTING OF STRUCTURAL CHROMOSOME ANOMALIES, FISH METHOD AND AREAS OF USE, REPORTING FISH RESULTS | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6008 | Non-coding Regions in the Genome | 3+0+0 | 8 |
| The students will be taught basic information about DNA regions that do not have code. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6009 | Cancer Genetics | 3+0+ | 8 |
| Molecular and genetic mechanisms in cancer. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6010 | Regulation of Gene Expression | 3+0+ | 8 |
| Examination of differentiation and gene expression in organisms at different organizational levels | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6011 | Biostatistics | 3+0+ | 8 |
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6012 | Scientific research techniques and publication ethics | 3+0+ | 8 |
| Scientific Research Designs Hypothesising Keeping Scientific Records Presentation of Data Scientific Report Writing Academic Publishing and Indexing Publication Ethics | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6013 | Epigenetics | 3+0+0 | 8 |
| Epigenetics: The New Science of Genetics, Mechanisms of DNA Methylation, Mechanisms of Histone Modifications, The Epigenetics of Non-coding RNA, Analysis of Gene-specific DNA Methylation/ Methods for Assessing Genome-wide DNA Methylation, DNA Hypomethylation in Cancer, Altered Histone Modifications in Cancer, Gene Regulation During Tumorigenesis, Epigenetic Regulation of miRNAs in Cancer, Epigenetic Regulation of miRNAs in Cancer, Epigenetic Changes During Cell Transformation, Epigenetic Reprogramming of Mesenchymal Stem Cells, Epigenetic Targeting Therapies to Overcome | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6014 | Molecular Techniques and Application Areas | 3+0+0 | 8 |
| USE OF PHENOL CHLOROFORM METHOD IN DNA ISOLATION, USE OF SPIN COLUMN METHOD IN DNA ISOLATION, USE OF MAGNETIC BEADS IN DNA ISOLATION, PCR AND MOST USED PCR TYPES, AGAROSE GEL ELECTROPHORESIS METHOD, SANGER SEQUENCE METHOD AND ITS AREAS OF USE, RFLP METHOD AND ITS USE AREAS, RNA TRACE PHENOL CHLOROFORM AND USE OF SPIN COLUMN METHOD, CDNA SYNTHESIS AND REAL TIME PCR TECHNIQUES AND AREAS OF USE, USE OF ACGH AND MLPA TECHNIQUES IN GENETIC DIAGNOSIS, NEW GENERATION SEQUENCING METHODS AND COMPARISON OF ALL SEQUENCING METHODS, METHODS USED IN MIRNA ISOLATION | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6016 | Types of Inheritance That Fit and Don't Follow Mendelian Rules | 3+0+0 | 8 |
| TERMS USED IN MEDICAL GENETICS, PEDIGREE DRAWING, GENERAL RULES OF AUTOSOMAL DOMINANT INHERITANCE, DISEASES WITH AUTOSOMAL DOMINANT INHERITANCE AND CLINICAL FEATURES, GENERAL RULES OF AUTOSOMAL RECESSIVE INHERITANCE, DISEASES WITH AUTOSOMAL RECESSIVE INHERITANCE AND CLINICAL FEATURES, GENERAL RULES OF X-LINKED DOMINANT INHERITANCE, DISEASES SHOWING X-LINKED DOMINANT INHERITANCE AND THEIR CLINICAL FEATURES, RULES OF X-LINKED RECESSIVE INHERITANCE, DISEASES AND CLINICAL FEATURES SHOWING X-LINKED RECESSIVE INHERITANCE, RULES AND DISEASES OF PSEUDOOTOSOMAL INHERITANCE, RULES AND DISEASES OF ATYPICAL MENDELIAN INHERITANCE, CHARACTERISTICS AND DISEASES OF MITECHONDRIAL INHERITANCE, GENETICS OF MULTIFACTORIALLY INHERITANT DISEASES | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6017 | Molecular Immunology | 3+0+0 | 8 |
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6018 | Tumor Heterogeneity and Drug Resistance | 3+0+0 | 8 |
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6102 | Tissue and Cell Culture | 3+0+0 | 8 |
| CELL CULTURE LAB. AND EQUIPMENTS, CELL CULTURE SAFETY RULES, PERIPHERAL BLOOD CELL CULTURE, BONE MARROW CELL CULTURE, AMNION CELL CULTURE, CVS CELL CULTURE, ABORT CELL CULTURE, 3D CELL CULTURE, STEM CELL CULTURE, PRIMARY CELL CULTURE, CANCER STEM CELL CULTURE, EX VIVO TISSUE CULTURE, EXPERIMENTAL ANIMAL MODELS | |||