The primary focus of Prof. Dr. Akdemir's research is the identification and optimization of innovative lead compounds for drug development. His research integrates molecular modeling and molecular pharmacology techniques. Following the completion of his doctoral studies, he assumed a position as a computational chemist within a pharmaceutical company. In 2011, he joined the Department of Pharmacology at the Faculty of Pharmacy, Bezmialem Vakıf University, as an assistant professor. He developed the pharmacy faculty curriculum and established the "Drug Discovery and Development" graduate progra...
The primary focus of Prof. Dr. Akdemir's research is the identification and optimization of innovative lead compounds for drug development. His research integrates molecular modeling and molecular pharmacology techniques. Following the completion of his doctoral studies, he assumed a position as a computational chemist within a pharmaceutical company. In 2011, he joined the Department of Pharmacology at the Faculty of Pharmacy, Bezmialem Vakıf University, as an assistant professor. He developed the pharmacy faculty curriculum and established the "Drug Discovery and Development" graduate programs and the Computational Drug Design research laboratory. As the Institutional Erasmus Coordinator, he secured the Erasmus and Erasmus+ charters. In 2013, he was appointed as the Vice Dean of the Faculty of Pharmacy. In 2023, he commenced his academic career at the Faculty of Pharmacy, Istinye University, and in July 2023, he was appointed as the Dean of the Faculty of Pharmacy. Prof. Dr. Akdemir has a publication record, with 64 research articles and 5 book chapters, and an H-index of 22.
Articles
The Synthesis, Anticancer Activity, Structure-Activity Relationships and Molecular Modelling Studies of Novel Isoindole-1,3(2H)-dione Compounds Containing Different Functional Groups ,2020
Thiosemicarbazone-benzene Sulfonamide Derivatives as Human Carbonic Anhydrases Inhibitors: Synthesis, Characterization, and In silico Studies ,2024
Synthesis and biological evaluation of new chloro/acetoxy substituted isoindole analogues as new tyrosine kinase inhibitors ,2020
Dithiocarbamates and dithiocarbonates containing 6-nitrosaccharin scaffold: Synthesis, antimycobacterial activity and in silico target prediction using ensemble docking-based reverse virtual screening ,2023
Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors ,2020
Reports
Evaluation of anti-inflammatory effect of novel fingolimod based compound F1-12h in SH-SY5Y, SK-N-SH and U-118MG cells for the efficancy in multiple sclerosis - ÇELİK TURGUT GURBET,DOYDUK DOĞUKAN,YILDIRIR YILMAZ,YAVUZ SERKAN,AKDEMİR ATİLLA,DİŞLİ ALİ,ŞEN ALAATTİN
Cytotoxic Effect of Novel 1-Ethyl and 2-Methyl Indole Derivatives on Breast Cancer Cells: ER and Aromatase as Their Potential Therapeutic Targets - İNCE ELİF,TAŞCIOĞLU ALİYEV ALEV,AKDEMİR ATİLLA,DURGUN KÜBRA,SÜZEN SİBEL,GÜRER ORHAN HANDE
Computer Aided Design and Synthesis of New Ursane Triterpenoids with Nuclear Factor Kappa B Inhibition Effect - ŞENOL HALİL,AKDEMİR ATİLLA,TOPÇU GÜLAÇTI
Nükleer Faktör Kappa-B İnhibisyon Etkili Ursan Türevi Triterpenlerin Sentezi - ŞENOL HALİL,TUNCAY SALİH,SEÇEN HASAN,ÖCAL NÜKET,AKDEMİR ATİLLA,TOPÇU GÜLAÇTI
Design and discovery of novel melatonin analogues as CYP1B1 inhibitors - İNCE ELİF,KARAASLAN ÇİĞDEM,AKDEMİR ATİLLA,SÜZEN SİBEL,GÜRER ORHAN HANDE
Books
Flavonoids and Phenolics. Medicinal Chemistry Lessons From Nature – Bentham Science Publisher
Medisinal Kimya Giriş – Ankara Nobel Tıp Kitab Evleri
Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications – Elsevier Science
Pharmacology of nicotinic acetylcholine receptors from the basic and therapeutic perspectives – Research Signpost
