Dr. Öğretim Üyesi Esma Nur Okatan 2006 yılında Gazi Üniversitesi Biyoloji Bölümünden birincilikle mezun olduktan sonra lisansüstü eğitimine Ankara Üniversitesi Tıp Fakültesi Biyofizik Anabilim dalında devam etmiştir ve yüksek lisans eğitimi süresince Tübitak tarafından desteklenmiştir (BİDEP 2228-A). 2009'da aynı bölümde araştırma görevlisi olarak atanarak (33-a) doktora eğitimine devam etmiştir. 2015 yılında doktora eğitimini tamamladıktan sonra Sivas Cumhuriyet Üniversitesinde akademik hayatına öğretim üyesi olarak devam etmiştir. Cumhuriyet Üniversitesi Tıp Fakültesi Araştırma Merkezi (Müdü...
Dr. Öğretim Üyesi Esma Nur Okatan 2006 yılında Gazi Üniversitesi Biyoloji Bölümünden birincilikle mezun olduktan sonra lisansüstü eğitimine Ankara Üniversitesi Tıp Fakültesi Biyofizik Anabilim dalında devam etmiştir ve yüksek lisans eğitimi süresince Tübitak tarafından desteklenmiştir (BİDEP 2228-A). 2009'da aynı bölümde araştırma görevlisi olarak atanarak (33-a) doktora eğitimine devam etmiştir. 2015 yılında doktora eğitimini tamamladıktan sonra Sivas Cumhuriyet Üniversitesinde akademik hayatına öğretim üyesi olarak devam etmiştir. Cumhuriyet Üniversitesi Tıp Fakültesi Araştırma Merkezi (Müdür yardımcısı) ve İleri Teknoloji Araştırma ve Uygulama Merkezinde (Western blot sistem sorumlusu) idari görevler almış ve protein analiz sistemlerini (western blot sistemi) hizmet verir duruma getirmiştir. 2015-2020 yılları arasında biri üniversite diğeri ise Türkiye Diyabet Vakfı (2016 En İyi Bilimsel Proje Ödülü kapsamında) tarafından desteklenen iki bireysel projeyi yürütücü olarak tamamlamıştır. In vivo ve in vitro deneysel diyabet/insulin direnci modellerinde araştırmalar gerçekleştirmiş ve diyabetik kardiyomiyopati/kardiyak insulin direncinin altında yatan elektrofizyolojik ve moleküler etkileşimleri incelemiştir. Dr. Öğretim Üyesi Esma Nur Okatan'ın Web of Science’ da taranan ve SSCI kapsamında 18 uluslararası araştırma makalesi bulunmaktadır ve bu makalelerin toplam atıf sayısı 396, h-endeksi 13 ve i10-endeksi 14’dür.
Makaleler
Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+and Ca2+and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
, 2014
ß Blocker Timolol Prevents Arrhythmogenic Ca2 Release and Normalizes Ca2 and Zn2 Dyshomeostasis in Hyperglycemic Rat Heart
, 2013
Selenium restores defective beta adrenergic receptor response of thoracic aorta in diabetic rats
, 2010
Profiling of cardiac adrenoceptor subtypes in the cardiac left ventricle of rats with metabolic syndrome Comparison with streptozotocin induced diabetic rats
, 2015
Omega 3E treatment regulates matrix metalloproteinases and prevents vascular reactivity alterations in diabetic rat aortaThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research
, 2009
Intracellular free zinc during cardiac excitation contraction cycle calcium and redox dependencies
, 2011
Interplay Between Cytosolic Free Zn2 and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes
, 2016
High carbohydrate diet induced myocardial remodelling in rats
, 2015
Enhancement of Cellular Antioxidant Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2 and Ca2 and Prevention of RyR2 Leak in Hyperglycemic Cardiomyocytes
, 2014
Doxycycline Ameliorates Vascular Endothelial and Contractile Dysfunction in the Thoracic Aorta of Diabetic Rats
, 2011
Cardioprotective effect of propranolol on diabetes induced altered intracellular Ca2 signaling in rat
, 2011
Antioxidants but not Doxycycline Treatments Restore Depressed Beta Adrenergic Responses of the Heart in Diabetic Rats
, 2009
title Electrophysiological basis of metabolic syndrome induced cardiac dysfunction sup 1 sup title
, 2016
Antioxidants but not Doxycycline Treatments Restore Depressed Beta-Adrenergic Responses of the Heart in Diabetic Rats
, 2009
The Contribution of Phosphodiesterases to Cardiac Dysfunction in High Carbohydrate Diet-Induced Metabolic Syndrome Rats
, 2019
Doxycycline Ameliorates Vascular Endothelial and Contractile Dysfunction in the Thoracic Aorta of Diabetic Rats
, 2011
Profiling of cardiac β-adrenoceptor subtypes in the cardiac left ventricle of rats with metabolic syndrome: Comparison with streptozotocin-induced diabetic rats
, 2015
Cardioprotective effect of propranolol on diabetes-induced altered intracellular Ca2 signaling in rat
, 2011
ß-Blocker Timolol Prevents Arrhythmogenic Ca2 Release and Normalizes Ca2 and Zn2 Dyshomeostasis in Hyperglycemic Rat Heart
, 2013
Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes
, 2016
Investigation on the cross talk between 3 Adrenergic receptor and Zn2 signalling indiabetic cardiomyocytes
, 2016
Electrophysiological basis of metabolic syndrome induced cardiac dysfunction title
, 2016
Cardioprotective effect of selenium via modulation of cardiac ryanodine receptor calcium release channels in diabetic rat cardiomyocytes through thioredoxin system
, 2013
Improvement of Functional Recovery of Donor Heart Following Cold Static Storage with Doxycycline Cardioplegia
, 2014
Age related regulation of excitation contraction coupling in rat heart
, 2011
High carbohydrate diet induced myocardial remodeling in rats
, 2015
Bildiriler
Monitoring of intracellular free Zn2+ and Ca2+ changes in cardiomyocytes from metabolic syndrome rats - TOY AYŞEGÜL,OKATAN ESMA NUR,DEĞİRMENCİ SİNAN,TURAN BELMA
An investigation on the antioxidant activity of azoramide, a promising new anti-diabetic, in palmitate-induced insulin resistance in H9c2 cells - OKATAN ESMA NUR
Beneficial Effects Of Azoramide On Palmitate-Induced Insulin Resistance In H9c2 - OKATAN ESMA NUR
Azoramidin Anti-Diyabetik Etkisinde İnsülinin Sinerjistik Rolü - OKATAN ESMA NUR
Mitochondria-directed approaches seem to play important role in the cellular therapy of cardiac dysfunction - OKATAN ESMA NUR,BİLLUR DENİZ,OLĞAR YUSUF,TUNCAY ERKAN,TURAN BELMA
Roles of oxidant stress and matrix metalloproteinases in endothelium- dependent relaxation of diabetic rat thorasic aorta - OKATAN ESMA NUR,BİLGİNOĞLU AYÇA,aydemir köksoy aslıhan,TURAN BELMA
Profiling of cardiac beta-adrenoceptor subtypes in left ventricle from metabolic syndrome rat heart: Comparison with streptozotocin-diabetic rat. - OKATAN ESMA NUR,TUNCAY ERKAN,TOY AYŞEGÜL,HAFEZ GAYE,TURAN BELMA
Yüksek karbonhidrat diyeti etkisinin sıçan kalbi ince-yapı bulguları ile gösterilmesi. - NAKKAŞ HİLAL,KIZIL ŞULE,OKATAN ESMA NUR,CAN BELGİN,TURAN BELMA
Doxycycline regulates intracellular zinc in diabetic rat heart via regulation of cellular redox cycle - TUNCAY ERKAN,OKATAN ESMA NUR,TURAN BELMA
Timolol treatment of diabetic rats improved basal cardiac function and responses to 3 but not 1 and 2 receptors stimulations - TUNCAY ERKAN,OKATAN ESMA NUR,TURAN BELMA
Depressed Sarcoplasmic Reticulum Activity Underlies Ca2 Dyshomeostasis in A Rat Model of Metabolic Syndrome - OKATAN ESMA NUR,TUNCAY ERKAN,TURAN BELMA
Intracellular Zn 2 Release Modulates Cardiac Ryanodine Receptor Function and Cellular Activity - OKATAN ESMA NUR,TUNCAY ERKAN,SEYMEN Aytac A,BİLGİNOĞLU AYÇA,SOZMEN Nazlı N,VASSORT Guy
Beneficial Effect Of Sodium Selenate On Vascular Dysfunction In Diabetic Rats International Societyfor Heart Research - OKATAN ESMA NUR,TANRIVERDİ Evrim,SEYMEN Aytaç A,TUNCAY ERKAN,GÜRDAL HAKAN,KÖKSOY Aslıhan,TURAN BELMA
Intracellular free Zn2 increase induces marked changes in mitochondrial function and ultrastructure in cardiac cells - TUNCAY ERKAN,OKATAN ESMA NUR,BİLLUR DENİZ,CAN BELGİN,TURAN BELMA
Intracellular free Zn2 increase induces marked changes in mitochondrial function and ultrastructure in cardiac cells - TUNCAY ERKAN,OKATAN ESMA NUR,BİLLUR DENİZ,CAN BELGİN,TURAN BELMA
Investigation on the cross talk between 3 Adrenergic receptor and Zn2 signalling in diabetic cardiomyocytes - TURAN BELMA,TUNCAY ERKAN,OKATAN ESMA NUR
Investigation on the cross talk between 3 Adrenergic receptor and Zn 2 signaling in diabetic cardiomyocytes - TUNCAY ERKAN,OKATAN ESMA NUR,TURAN BELMA
Intracellular free Zn2 increase induces marked changes in mitochondrial function and ultrastructure in cardiac cells - TUNCAY ERKAN,OKATAN ESMA NUR,BİLLUR DENİZ,CAN BELGİN,TURAN BELMA
Monitoring of intracellular free Zn2 and Ca2 changes in cardiomyocytes from metabolic syndrome rats - TOY AYŞEGÜL,OKATAN ESMA NUR,DEĞİRMENCİ SİNAN,TURAN BELMA
Depressed Sarcoplasmic Reticulum Activity Underlies Ca2 Dyshomeostasis in A Rat Model of Metabolic Syndrome - OKATAN ESMA NUR,erkan tuncay,TURAN BELMA
Monitoring of intracellular free Zn2 and Ca2 changes in cardiomyocytes from metabolic syndrome rats - TOY AYŞEGÜL,OKATAN ESMA NUR,DEĞİRMENCİ SİNAN,TURAN BELMA
Depressed Sarcoplasmic Reticulum Activity Underlies Ca2 Dyshomeostasis in A Rat Model of Metabolic Syndrome - OKATAN ESMA NUR,Tuncay Erkan,TURAN BELMA
Alterated Intracellular Calcium Ion Regulation Plays Important Role in High Carbohdyrate Intake Induced Myocardial Remodeling - OKATAN ESMA NUR,TOY AYŞEGÜL,TURAN BELMA
Diyabetli sıçan damar düz kası A1 Adrenerjik yanıtlarında matriksmetalloproteinazlar ve oksidan stresin rolü - OKATAN ESMA NUR,TURAN BELMA
Roles of oxidant stress and matrix metalloproteinases in endothelium dependent relaxation of diabetic rats - OKATAN ESMA NUR,TURAN BELMA
Role of intracellular zinc on phosphorylation level of cardiac ryanodineReceptors in normoglycemic and hyperglycemic rats - OKATAN ESMA NUR,TURAN BELMA
EFFECTS OF ASTRAGALUS EXTRACT ON OXIDANT ANTIOXIDANT STATUS AND MYOCARDIAL CONTRACTILITY IN STREPTOZOCIN INDUCED DIABETIC RATS - NAMUSLU MEHMET,OKATAN ESMA NUR,TURAN BELMA,DURAK İLKER
Beneficial role of selenium on diabetes induced altered adrenergic receptorresponse of aortic smooth muscle of the rats - OKATAN ESMA NUR,TURAN BELMA
Oxidative stress plays important role on cardiac ryanodine receptor calciumrelease channels in diabetic rats - OKATAN ESMA NUR,TURAN BELMA
Cardioprotective effect of sodium selenate or thioredoxin through ryanodinereceptor modulation - OKATAN ESMA NUR,TURAN BELMA
Investigation of in vitro effect of timolol on sarcoplasmic reticulum functionin streptozotocin induced diabetic rat heart - OKATAN ESMA NUR,TURAN BELMA
Metabolik sendromlu sıçanlarda kalbin elektriksel ve mekanik aktivitesi üzerine bir çalışma - OKATAN ESMA NUR,TURAN BELMA
An electrophysiological investigation on cardiac function from ratssupplemented with high carbohydrate diet - OKATAN ESMA NUR,TURAN BELMA
Yüksek Sükrozla İndüklenen Metabolik Sendromlu Sıçan Kardiyomiyositlerinde Hücre İçi Ca2 Homeostazına Etkili Faktörlerin İncelenmesi - OKATAN ESMA NUR,TURAN BELMA
Yüksek Sükrozla İndüklenen Metabolik Sendromlu Sıçan Kardiyomiyositlerinde Hücre İçi Ca2 Homeostazına Etkili Faktörlerin İncelenmesi - OKATAN ESMA NUR,TURAN BELMA
Timolol Treatment of Diabetic Rats Improved Basal Cardiac Function and Responses to 3 but not 1 and 2 receptors Stimulations - TUNCAY ERKAN,OKATAN ESMA NUR,TURAN BELMA
A Comparative Study on Beneficial Effects of Antioxidants on Diabetes induced Cardiac Contractile Dysfunction - TUNCAY ERKAN,TURAN BELMA
Increased Oxidative Stress Triggers Marked Intracellular Zinc Elevation in Cardiomyocytes Under Hyperglycemia - TUNCAY ERKAN,LYON Alexander R,RUTTER Guy A,TURAN BELMA
Hücre İçi Serbest Zn 2 nun Kardiyomiyositlerde Uyarılma Kasılma Çiftlenimindeki Rolü - TUNCAY ERKAN,OKATAN ESMA NUR,TURAN BELMA
Determination of Cytosolic Endoplasmic Reticulum and Mitochondrial Free Zinc Levels in Cardiomyocytes by Using Genetically Encoded Zinc Sensitive FRET Sensors - TUNCAY ERKAN,LYON Alexander R,TURAN BELMA,RUTTER Guy A
Ödüller
TÜRKİYE DİYABET VAKFI DIABETES MELLITUS BİLİMSEL PROJE DESTEK ÖDÜLÜ – 2016
