Aslı Kutlu completed her undergraduate studies at the Department of Chemical and Biological Engineering at Koç University in 2012. In 2012, she started her Ph.D. studies at the Department of Molecular Biology, Genetics and Bioengineering. Sabancı University under the supervision of Prof. Uğur Sezerman. Her research studies are about protein engineering for industrial applications. After receiving her Ph.D. in 2017, she worked as a post-doctoral fellow at Acıbadem Mehmet Aydınlar University, Department of Medical Statistics and Bioinformatics, School of Medicine, where she joined the Sezerman l...
Aslı Kutlu completed her undergraduate studies at the Department of Chemical and Biological Engineering at Koç University in 2012. In 2012, she started her Ph.D. studies at the Department of Molecular Biology, Genetics and Bioengineering. Sabancı University under the supervision of Prof. Uğur Sezerman. Her research studies are about protein engineering for industrial applications. After receiving her Ph.D. in 2017, she worked as a post-doctoral fellow at Acıbadem Mehmet Aydınlar University, Department of Medical Statistics and Bioinformatics, School of Medicine, where she joined the Sezerman lab again. During the postdoctoral fellowship, she mainly focused on studying the mechanism of rare diseases through molecular dynamics (MD) studies to elucidate the role of novel mutations. Between February 2019 and August 2020, she worked at Biruni University as an assistant professor. In September 2020, she joined the ISU Department of Molecular Biology and Genetics as a PI in the field of molecular cancer research and rare disease mechanism through experimental and computational approaches.
Articles
TNFRSF13B VARIANTS ACT AS MODIFIERS TO CLINICAL PHENOTYPES IN COMMON VARIABLE IMMUNE DEFICIENCY DISORDERS
, 2023
Contributing to the Functional Classification of Missense Variants in RAG1 Protein from Structural Perspective
, 2025
Fc–FcγRI Complexes: Molecular Dynamics Simulations Shed Light on Ectodomain D3′s Potential Role in IgG Binding
, 2024
Elucidating the roles of naturally occurring silent mutations in Polycystic Ovary Syndrome (PCOS)
, 2020
A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia
, 2019
Understanding the impacts of self-shuffling approach on structure and function of shuffled endoglucanase enzyme via MD simulations
, 2020
Repurposing Fc gamma receptor I (FcγRI, CD64) for site-oriented monoclonal antibody capture: A proof-of-concept study for real-time detection of tumor necrosis factor-alpha (TNF -α)
, 2023
Identifying and elucidating the roles of Y198N and Y204F mutations in the PAH enzyme through molecular dynamic simulations
, 2021
Identification of key genes and pathways for cholangiocarcinoma using an integrated bioinformatics analysis
, 2022
Discussing the roles of proline and glycine from the perspective of cold adaptation in lipases and cellulases
, 2022
Computational analysis of missense filamin-A variants, including the novel p.Arg484Gln variant of two brothers with periventricular nodular heterotopia.
, 2022
Enhancing Enzymatic Properties of Endoglucanase I Enzyme from Trichoderma Reesei via Swapping from Cellobiohydrolase I Enzyme
, 2019
Performing the comparative analysis to understand the functional roles of genes in different pathways of cardiomyopathy disease
, 2021
A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia
, 2019
Investigating the structural properties of the active conformation BTL2 of a lipase from Geobacillus thermocatenulatus in toluene using molecular dynamic simulations and engineering BTL2 via in-silico mutation
, 2018
Enhancing Enzymatic Properties of Endoglucanase I Enzyme from Trichoderma Reesei via Swapping from Cellobiohydrolase I Enzyme
, 2019
Desing and characterization of two novel cellulases through single gene shuffling of Cel12A (EG3) gene from Trichoderma reesei
, 2016
Reports
Hydrogen Bond Fingerprints: Revealing the Complexities of Protein Function - ÇETİN EBRU, BERKSÖZ MELİKE, KUTLU ASLI, ATILGAN CANAN, ATILGAN ALİ RANA
Modeling Structural Properties and Thermostability of the Active Conformation of Lipase from Geobacillus Thermocatenulatus, BTL2, in Organic Solvent. - KUTLU ASLI,Venturini Alessandro,BURDUROĞLU HÜSEYİN CAHİT,SEZERMAN OSMAN UĞUR
Yaygın Değişken İmmün Yetersizliklerde Tüm Genom Metilasyon Değişimlerinin
İncelenmesi - Işıkgil Begüm,BİLGİÇ ELTAN SEVGİ,ERBİLGİN YÜCEL,KUTLU ASLI,GEMİCİ KARAASLAN HATİCE BETÜL,ÖZEK ESRA,KIYKIM AYÇA,YILMAZ AYDOĞAN HÜLYA,BARIŞ SAFA,AYDINER ELİF,AR MUHLİS CEM,ÖZEN AHMET OĞUZHAN,SAYİTOĞLU MÜGE,FIRTINA SİNEM
Generation of novel cellulases and lipases for industrial applications through DNA shuffling and molecular dynamic simulations - KUTLU ASLI, SEZERMAN OSMAN UĞUR
“MASP2 geninde meydana gelen sessiz varyantların biyoinformatik analizi - Işıkgil Begüm, FIRTINA SİNEM, KUTLU ASLI
Explaining the Different Forms of Primer Immunodeficiency (PID) Caused by Missense Variants in RAG1 Gene from Structural Perspective
- Işıkgil Begüm, FIRTINA SİNEM, KUTLU ASLI
How To Use Big Data In Health Informatics For Discovery Of Diagnostics and Prognostic Biomarkers In Cancer? - Arda Merve, ATAK EVREN, KUTLU ASLI
How To Utilize Gene Expression Omnibus (GEO) Data Sets In Pathway-Based Biomarker Studies: Cholangiocarcinoma Case - Arda Merve, KUTLU ASLI, ATAK EVREN, ULUKAYA ENGİN
Head and Neck cancer: performing functional gene enrichment and clustering study to discover the new potentials as biomarker - Atak Evren,Öten Ahmet Melih,İRİGÜL SÖNMEZ ÖYKÜ,YENENLER ASLI
Database application on cardiomyopathy - YENENLER ASLI,Serttürk Seda
Using a decision tree meta-predictor and accelerated molecular dynamics method together to predict the functional impacts of variants - Gerlevik Umut, Yenenler Aslı, Ülgen Ege, Sezerman Osman Uğur
Kolanjiokarsinomda secili genlerin potansiyel biyobelirtec rollerinin hesaplamali yaklasimla yeniden gozden gecirilmesi - KUTLU ASLI
Probing for potential genes as novel biomarkers in head-and-neck cancer: prognostic and diagnostic approach - ATAK EVREN, KUTLU ASLI
Probing The Structural Impacts Of Arg388 Replacements In Pkp2 Protein Complex: Spesıfıc Case In Arvc - KUTLU ASLI, Sahin Şuara, Özkan Mehmet Emre, ULUKAYA ENGİN
Bioinformatics Approach Of The Effect Of Radıochemotherapy Treatment On Gene Expression - ATAK EVREN, ULUKAYA ENGİN, KUTLU ASLI
Revealing the structural impacts of point mutations on MeCP2 protein associated with Rett Syndrome via MD Simulations - Öten Ahmet Melih, KUTLU ASLI
Head-and-neck cancer: performin functional gene enrichment and clustering study to discover the new potentials as biomarker - Atak Evren, Öten Ahmet Melih, İRİGÜL SÖNMEZ ÖYKÜ, KUTLU ASLI
SCRAPIE RELATED MUTATIONSANALYSES OF SHEEP PRION PROTEIN VIA MOLECULAR DYNAMICS SIMULATIONS - Uyar Meryem Sinem, Öten Ahmet Melih, Erdoğan İlayda, İRİGÜL SÖNMEZ ÖYKÜ, KUTLU ASLI
Analysis of Cold-Adaptive Lipases with Molecular Dynamics Simulations - Erdoğan İlayda, Öten Ahmet Melih, KUTLU ASLI
The investigation of activation mechanism of BTL2 in non-aqueous solvents - KUTLU ASLI, SEZERMAN OSMAN UĞUR
Generation of cellulases for industrial applications through DNA shuffling - KUTLU ASLI, SEZERMAN OSMAN UĞUR
An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - Gerlevik Umut, KUTLU ASLI, SEZERMAN OSMAN UĞUR
An attempt to identify the potential biomarkers in the Bladder Cancer via functional gene-enrichment approach - elbeyoğlu şeyma, Öten Ahmet Melih, Atak Evren, özgürses mete emir, İRİGÜL SÖNMEZ ÖYKÜ, KUTLU ASLI
Head-and-neck cancer: Performing functional gene enrichment study to discover the new potentials as biomarkers - Atak Evren, Öten Ahmet Melih, elbeyoğlu şeyma, özgürses mete emir, İRİGÜL SÖNMEZ ÖYKÜ, KUTLU ASLI
Head-and-neck cancer: Performing functional gene enrichment study to discover the new potentials as biomarker - Atak Evren,Öten Ahmet Melih,elbeyoğlu şeyma,özgürses mete emir,İRİGÜL SÖNMEZ ÖYKÜ,YENENLER ASLI
Gene enrichment analysis to elucidate the role of mitochondrial genes in prostate cancer - özgürses mete emir, Öten Ahmet Melih, İRİGÜL SÖNMEZ ÖYKÜ, KUTLU ASLI
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
PRaMP: An attempt to improve the accuracy of mutation impact prediction through molecular dynamics studies - YENENLER ASLI,Gerlevik Umut,Ülgen Ege,sezerman osman uğur
Head and Neck cancer: performing functional gene enrichment and clustering study to discover the new potentials as biomarker - Atak Evren,Öten Ahmet Melih,İRİGÜL SÖNMEZ ÖYKÜ,YENENLER ASLI
Database application on cardiomyopathy - YENENLER ASLI,Serttürk Seda
Books
Metabolic Syndrome: A compherensive update with new insights – Bentham Books
Lippincott’s Illustrated Reviews: Biochemistry, Eighth Edition – Nobel Tıp
Lippincott’s Illustrated Reviews: Biochemistry, Eighth Edition – Nobel Tıp
Moleküler Biyoloji Güncel Araştırma Teknikleri – Ema Tıp Kitabevi
TÜM YÖNLERİYLE DİL VE KONUŞMA BOZUKLUKLARINDA DEĞERLENDİRME – AKADEMİSYEN YAYINEVİ
