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Academic Member

Assoc. Prof. Muradiye Acar

Dahili Tıp
Muradiye ACAR has completed Bachelor’s degree in Department of Biology, Faculty of Science, Selcuk University with the best second student degree in 2002. Muradiye ACAR had MSc. degree in 2005, and her PhD in 2012 in Selcuk University Medical Genetics program. She has 4 gold and 1 silver medals from the iGEM (International genetically engineered machines) competition organized by MIT between 2011-2015. Dr. Acar has many international publications. She has worked as an executive and researcher in 14 research projects, 4 of which are TUBITAK projects. She is a member of Medical Genetics Associat...
Muradiye ACAR has completed Bachelor’s degree in Department of Biology, Faculty of Science, Selcuk University with the best second student degree in 2002. Muradiye ACAR had MSc. degree in 2005, and her PhD in 2012 in Selcuk University Medical Genetics program. She has 4 gold and 1 silver medals from the iGEM (International genetically engineered machines) competition organized by MIT between 2011-2015. Dr. Acar has many international publications. She has worked as an executive and researcher in 14 research projects, 4 of which are TUBITAK projects. She is a member of Medical Genetics Association, MOKAD and EACR. Dr. Acar has been in the academic staff of Istinye University, Faculty of Medicine, Department of Medical Genetics since 2018.

Articles

  • Cancer stem cell isolation and characterization from lung cancer cells ,2023
  • The effects of salidrosid on DIABLO and XAF1 gene expression in PC3 prostat cancer cells ,2014
  • A potential association between the number of CA repeats in the promoter region of the ADAMTS9 gene with lymphatic metastasis of breast cancer ,2013
  • Boric acid’s cytotoxic effect on CD133⁺ cancer stem cells in H460 cell line ,2023
  • Novel RUNX1 Variation in B-cell Acute Lymphoblastic Leukemia. ,2023
  • Investigation of the effects of 5-fluorouracil and thymoquinone on head and neck cancer stem cells ,2015
  • A comparative study of Bulgarian and Turkish Asphodeline lutea root extracts: HPLC-UV profiles, enzyme inhibitory potentials and anti-proliferative activities against MCF-7 and MCF-10A cell lines ,2015
  • Matrix Metalloproteinases 2 and 9 Polymorphism in Patients With Myeloproliferative Diseases A STROBE-Compliant Observational Study ,2015
  • The effect of survivin gene promoter polymorphism on breast cancer ,2014
  • Gene Expression Profiles of Tumor Necrosis Factor-α and Endothelin-1 in Obstructive Sleep Apnea ,2019
  • The effects and interactions of APOE and APH-1A polymorphisms in Alzheimer disease ,2015
  • Is There a Relationship Between Pelvic Organ Prolapse and Tissue Fibrillin-1 Levels? ,2015
  • Relationship between cytosine-adenine repeat polymorphism of ADAMTS9 gene and clinical and radiologic severity of knee osteoarthritis ,2018
  • Prevalence of human papilloma virus types in Turkish and Albanian women ,2018
  • Functional analysis of ESM1 by siRNA knockdown in primary and metastatic head and neck cancer cells ,2018
  • Investigation of the expression of RIF1 gene on head and neck, pancreatic and brain cancer and cancer stem cells ,2016
  • Potential genetic biomarkers in the early diagnosis of Alzheimer disease: APOE and BIN1 ,2015
  • Analysis of promoter methylation of Dickkopf1 (DKK1) gene in breast cancer ,2012
  • Loss of heterozygosity in ING3 and ING5 genes in breast cancer ,2014
  • HLA-B27 subtypes in Turkish patients with ankylosing spondylitis and healthy controls ,2012
  • The role of human Dectin-1 Y238X gene polymorphism in recurrent vulvovaginal candidiasis infections ,2014
  • Association of 5-HT1A and 5-HT1B Gene Polymorphisms with Obsessive-Compulsive Disorder in a Turkish Population ,2016
  • The effects of hypericin on ADAMTS and p53 gene expression in MCF-7 breast cancer cells ,2014
  • Serum and aqueous xanthine oxidase levels, and mRNA expression in anterior lens epithelial cells in pseudoexfoliation ,2015
  • A Novel Ganciclovir Resistance Mutation in the UL97 Gene of the HHV-5 in an Adult Hematopoietic Stem Cell Transplant Recipient ,2017
  • Effect of hypericin on the ADAMTS-9 and ADAMTS-8 gene expression in MCF7 breast cancer cells ,2013
  • The Role of ADAMTS9 Gene Promoter (Ca) Repeat in Developmental Hip Dysplasia ,2015
  • Pankreas Kanseri Hücrelerinde Tripartite Motif-Containing Protein 3 (TRIM3) Gen Ekspresyonunun Araştırılması ,2022
  • The Effects of Caffeic Acid Phenethyl Ester (CAPE), Royal Jelly, and Curcumin on Gene Expression of ADAMTS-1, -5, and -9 in OUMS-27 Chondrosarcoma Cells: A Preliminary Study ,2013

Reports

  • Pelvik Organ Prolapsusu İle Doku Fibrillin-1 Seviyeleri Arasında İlişki Var Mı? - ESER AYLA, ÜNLÜBİLGİN EYLEM, HIZLI FATİH, ACAR MURADİYE, KAMALAK ZEYNEP, KÖŞÜŞ AYDIN, KÖŞÜŞ NERMİN, HIZLI DENİZ, GÜNDÜZ ESRA
  • The Relationship Between Cytosine Adenine Repeat Polymorphism In The Promoter Regionofadamts9 A Distintegrinand Metalloproteinase With Thrombospondin Motif 9 Gene Andclinical And Radiologic Severity Of Knee Osteoarthritis - GÖK KEVSER, CEMEROĞLU ÖZLEM, ÇAKIRBAY HAŞİM, GÜNDÜZ ESRA, ACAR MURADİYE, ÇETİN ELİF NİHAN, GÜNDÜZ MEHMET, DEMİRCAN KADİR
  • The Anti Cancer Activity Of Propolis In Colorectal Cancer - GÜNDÜZ MEHMET, GÖKHAN NAS, ACAR MURADİYE, HATİPOĞLU ÖMER FARUK, YILMAZ BURAK, KAYA GÜLHAN, GÜNDÜZ ESRA
  • The effects of hypericin on p53 and ADAMTS gene expression inMCF 7 breast cancer cell line - ACAR MURADİYE, OCAK ZEYNEP, ERDOĞAN KÜBRA, ÇETİN ELİF NİHAN, HATİPOĞLU ÖMER FARUK, ÜYETÜRK UMMUGUL, GÜNDÜZ ESRA, GÜNDÜZ MEHMET
  • Investigation of the Role of ING1 splice variants p24ING1 and p33ING1 in carcinogenesis and metastasis of head and neck cancer - GÜNDÜZ ESRA,GÜNDÜZ MEHMET,ACAR MURADİYE,BENDER ONUR,MOROSKİ ERKUL CATHERİNE,HATİPOĞLU ÖMER FARUK
  • Effect of boric acid on head and neck cancer cell lines - GÜNDÜZ MEHMET,ACAR MURADİYE,FAKİOĞLU KÜBRA,DOĞAN BİRSEN,ÖZNUR MURAT,GÜNDÜZ ESRA
  • Effect of Survivin gene 1547 A G rs3764383 polymorphismin Turkish breast cancer patients - ACAR MURADİYE,ŞAHİN HÜSEYİN,ÖZNUR MURAT,BENDER ONUR,SÜRGİT ÖNDER,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Mutation Analysis of ESM 1 Gene in Breast Cancer Patient Tissues - DEDE SERAP,ACAR MURADİYE,ÖZNUR MURAT,GÖKHAN NAS,HATİPOĞLU ÖMER FARUK,GÜNDÜZ MEHMET,GÜNDÜZ ESRA
  • Overexpression of microRNAs May Be Key to Decreased Autophagy and PRR in the Pathogenesis of Focal Segmental Glomerulosclerosis - BAVBEK NUKET,AKDENİZ DERYA,YILMAZ HAKKI,YILDIRIM ÜMRAN,BENDER ONUR,FIRAT ZEHRA,ACAR MURADİYE,HATİPOĞLU ÖMER FARUK,BİLGİÇ MUKADDER AYŞE,GÜNDÜZ ESRA,AKÇAY ALİ
  • Identification and characterisation of pancreatic cancer stem cells - ACAR MURADİYE,YILDIRIM KÜBRA,GÜNDÜZ ESRA,DOĞAN MİKAİL,HATİPOĞLU ÖMER FARUK
  • Evaluation of anti tumor effect of combined use of thymoquinonewith mitoxantrone in YKG1 glioma cells - ÖZNUR MURAT,HATİPOĞLU ÖMER FARUK,ACAR MURADİYE,YILMAZ BURAK,KARAGÖZ EMRAH,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Genetic association of 5 HT1A and 5 HT1B gene polymorphisms with OCD in the Turkish population - ALDEMİR SEÇİL,ACAR MURADİYE,OCAK ZEYNEP,DALBUDAK ERCAN,YİĞİTOĞLU MUHAMMET RAMAZAN,GÜNDÜZ ESRA
  • The development of a novel hypoxia inducible system to treat cardiovascular diseases caused by ischemia - GÜNDÜZ MEHMET, ÇİĞDEM SADIK, ÇELİK A., KAYA T., ERYONUCU B., ACAR MURADİYE, GÜNDÜZ ESRA
  • The relationship between alcohol dependence and prodynorphin gene polymorphisms among Turkish men - DALBUDAK ERCAN, EVREN CÜNEYT, ACAR MURADİYE, GÜNDÜZ ESRA, YİĞİTER SERA, GÜNDÜZ MEHMET, ALDEMİR SEÇİL
  • Prodynorphin gene polymorphisms are not related with heroin dependency among Turkish men: a pilot study - DALBUDAK ERCAN, EVREN CÜNEYT, ACAR MURADİYE, GÜNDÜZ ESRA, ÇETİN TURAN, GÜNDÜZ MEHMET, ALDEMİR SEÇİL
  • The Effects Of Sali̇drosi̇d On Diablo And Xaf1 Gene Expressi̇on In Pc3 Prostate Cancer Cells - OCAK ZEYNEP,ÜYETÜRK UĞUR,ACAR MURADİYE,ETLİK ÖZDAL,TEKELİOĞLU VİLDAN,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Link Between ADAMTS9 Aggrecanase Gene and Breast Cancer - ACAR MURADİYE,AŞIK FATMA,DEMİRCAN KADİR,BOZER MİKDAT,HALTAŞ HACER,YENİDÜNYA SİBEL,GÜNDÜZ ESRA,GÜNDÜZ MEHMET,YİĞİTOĞLU MUHAMMET RAMAZAN
  • Investigation of Microsatellite Instability in Colorectal Cancer Patients - ACAR MURADİYE
  • Mutation Status of P53 in Head and Neck Squamous Cell Carcinoma - GÜNDÜZ ESRA,GÖKHAN NAS,ACAR MURADİYE,DEDE SERAP,ERDOĞAN KÜBRA,MOROSKİ ERKUL CATHREİNE,GÜNDÜZ MEHMET
  • The effects of caffeic acid phenethyl ester CAPE royal jelly and curcumin on gene expression of ADAMTS1 5 and 9 in OUMS 27 chondrosarcoma cells - AKYOL SÜMEYYA,ACAR MURADİYE,ZAHİDE NUR ÜNAL,HASGÜL RUKİYE,SERPİL ERDOĞAN,DEMİRCAN KADİR,AKYOL ÖMER,YİĞİTOĞLU MUHAMMET RAMAZAN
  • Examination Of Cell-Free DNA Mutations In Lung Cancer Patients By Next-Generation Sequencing Method - ACAR MURADİYE
  • Cytotoxıc Effect Of Boric Acid On Cancer Stem Cells In Lung Cancer - ACAR MURADİYE
  • Tarama Testinden Preimplantasyon Genetik Tanıya Doğru Sma Hastalığı: Önlenebilir Bir Halk Sağlığı Problemi Midir? - ACAR MURADİYE
  • IL 1 up regulates ADAMTS9 mRNA expression in cancer cells - ZAHİDE NUR ÜNAL,AKYOL SÜMEYYA,ACAR MURADİYE,UÇAR FATMA,KAYA GÜLHAN,YİĞİTOĞLU MUHAMMET RAMAZAN,GÜNDÜZ ESRA,DEMİRCAN KADİR
  • Ailesel Akdeniz Ateşi Fmf Tespit Edilen Olgularda Tlr 2 Tlr 4 Saa1 Gen Polimorfizmlerinin Amiloidozis Ve Kolşisin Direnci Gelişimi Üzerine Olan Etkisi - OCAK ZEYNEP,ACAR MURADİYE,TARIK OCAK,ETLİK ÖZDAL,DOĞAN HASAN,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Erkek İnfertilitesi İle Spermatogenez Gen Polimorfizmlerinin İlişkisi - OCAK ZEYNEP,ACAR MURADİYE,ÜYETÜRK UĞUR,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Glioma Kök Hücre İzolasyonu Ve Karakterizasyonu - ÖZNUR MURAT,DEMİR ESİN,HATİPOĞLU ÖMER FARUK,ACAR MURADİYE,ÇİĞDEM SADIK,YİĞİTOĞLU BEYZA NUR,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • İnsan Kondrosit Ve Oums 27 Kondrosarkom Hücre Kültürlerinde Ankaferd Kullanımının Etkinliği - OCAK ZEYNEP,OCAK TARIK,ACAR MURADİYE,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • The relationship between breast cancer and Tetraspanin8 TSPAN8 gene polymorphism - ACAR MURADİYE,YILMAZ TÜLİN,ÖZNUR MURAT,ÜNAL ZAHİDE,GÜNDÜZ ESRA,GÜNDÜZ MEHMET
  • Sıçan Epilepsi Modelinde Cep Telefonu Radyasyonu Maruziyetinin Scn1a Geni Üzerine Etkileri - GÜLTOP KEBİRET,ACAR MURADİYE,GÜLTOP FETHİ,İLHAN ATİLLA,GÜNDÜZ MEHMET,GÜLER FAZİLET,YİĞİTOĞLU MUHAMMET RAMAZAN,GÜNDÜZ ESRA
  • Gebeliğe Bağlı Oluşan Strialı Hastalarda Matriks Metalloproteinaz 2 Ve MatriksMetalloproteinaz 9 Polimorfizminin Analizi - KAYA GÜLHAN,İNEGÖL GÜMÜŞ İLKNUR,ACAR MURADİYE,KAYA MEHMET,GÜNDÜZ MEHMET,GÜNDÜZ ESRA

Books

  • Tıp, Hemşirelik ve Sağlık Bilimlerine İnovatif Yaklaşımlar: Dinamikler ve Değişimler – Özgür Yayınları
  • Omics for Personalized Medicine – Springer
  • Noninvasive Molecular Markers in Gynecologic Cancers – Taylor & Francis/CRC Press
  • Omics Approaches in Breast Cancer - Towards nextgeneration diagnosis prognosis and therapy – Springer
  • A Concise Review of Molecular Pathology of Breast Cancer – Intech Open

Awards

  • Silver medal – 2015
  • Gold medal – 2014
  • Gold medal – 2013
  • Best natural biobrick – 2011
  • Gold Medal – 2011
  • Bronze Award – 2012
  • BÖLÜM İKİNCİLİĞİ – 2002
Assoc. Prof. Muradiye Acar - İstinye Üniversitesi
muradiye.acaristinye.edu.tr
SW

Research Areas

  • Sağlık Bilimleri Temel Alanı
  • Tıbbi Genetik

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