Dr. Ali Tuğrul Akin graduated from the Department of Biology at Erciyes University, Faculty of Science, in 2012. He completed his master's degree at the Institute of Science at the same university and obtained his Ph.D. in 2021 with his dissertation titled "Histological and Molecular Investigation of Pluripotency in Adriamycin-Induced Testicular Damage." He conducted his postdoctoral research at the Erciyes University Drug Application and Research Center, where he established his own laboratory and research team. In 2023, he carried out postdoctoral studies at King’s College London under the T...
Dr. Ali Tuğrul Akin graduated from the Department of Biology at Erciyes University, Faculty of Science, in 2012. He completed his master's degree at the Institute of Science at the same university and obtained his Ph.D. in 2021 with his dissertation titled "Histological and Molecular Investigation of Pluripotency in Adriamycin-Induced Testicular Damage." He conducted his postdoctoral research at the Erciyes University Drug Application and Research Center, where he established his own laboratory and research team. In 2023, he carried out postdoctoral studies at King’s College London under the TÜBİTAK 2219 International Postdoctoral Research Fellowship Program. In 2024, he joined the Cancer and Pharmaceutical Science department at the same university as a postdoctoral researcher, focusing on Chronic Lymphocytic Leukemia (CLL) and Acute Promyelocytic Leukemia (APL). His research interests include cancer epigenetics, epigenetic modifications, DNA damage and replication, and pharmaceutical drug targets
Articles
The Ameliorative Effects of Caffeic Acid Phenethyl Ester in Cisplatin-Induced Nephrotoxicity: Assessment of the Oxidative Stress an Inflammation
, 2021
Edaravone attenuates doxorubicin-induced oral mucosal injury via modulation of oxidative stress, inflammatory signaling, and the SIRT1/TLR4/NF-kB/ACE2 axis in rats
, 2025
Anti-inflammatory and anti-apoptotic effects of naringin on bacterial endotoxin-induced small intestine damage in rats
, 2022
Thymoquinone reduces methotrexate-induced heart damage: a histopathological study in rats
, 2023
Protective effect of melatonin on cisplatin-induced liver injury in rats
, 2022
Electrophysiological, histopathological, and biochemical evaluation of the protective effect of probiotic supplementation against pentylenetetrazole‐induced seizures in rats
, 2022
Evaluation by different mechanisms of the protective effects of vitamin B12 on methotrexate nephrotoxicity
, 2021
Therapeutic effects of thymoquinone in doxorubicin-induced hepatotoxicity via oxidative stress, inflammation and apoptosis
, 2021
Türkiye akar faunası için yeni bir kayıt Eremobelba geographica Berlese 1908 Acari Oribatida
, 2015
Oribatid mite fauna (Acari) of the Çat Forest (Sivas, Turkey)
, 2017
Effects of vitamin B12 on methotrexate hepatotoxicity: evaluation of receptor-interacting protein (RIP) kinase
, 2020
Histological evaluation of the effects of rapamycin and 3-methyladenine on cisplatin-induced epididymal injury in rats
, 2021
Probiotic supplementation alleviates absence seizures and anxiety- and depression-like behavior in WAG/Rij rat by increasing neurotrophic factors and decreasing proinflammatory cytokines
, 2022
Chloroquine Decreased Kir6.2 Immunoreactivity in Chronic Hypoxic Heart
, 2022
Chloroquine attenuates chronic hypoxia‐induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
, 2022
The protective effect of Origanum majorana essential oil on gentamicin-induced nephrotoxicity in rats.
, 2021
Thymoquinone alleviates doxorubicin induced acute kidney injury by decreasing endoplasmic reticulum stress, inflammation and apoptosis
, 2022
Investigation of the effect of Chloroquine on Adriamycin-induced kidney damage
, 2022
Histopathological Changes In Lung Tissue Caused By Diabetes: A Review
, 2022
Immunoreactivity of Kir3.1, muscarinic receptors 2 and 3 on the brainstem, vagus nerve and heart tissue under experimental demyelination
, 2023
Therapeutic effect of thymoquinone on brain damage caused by nonylphenol exposure in rats
, 2023
Effects of adriamycin on cell differentiation and proliferation in rat testis
, 2023
Thymoquinone attenuates doxorubicin-induced lung damage via heat shock proteins, inflammation and endoplasmic reticulum stress
, 2023
Investigation of the effect of thymoquinone on kidney damage in isoproterenol-induced myocardial infarction in rats and cardiorenal interactions
, 2023
Protective effect of melatonin on cisplatin induced acute kidney injury: Role of regulation of heat shock proteins expressions
, 2023
In vivo Gonadoprotective Effects of Myricetin on Cisplatin- Induced Testicular Damage via Suppression of TLR4/NF-kB Inflammation Pathway and Heat-Shock Response
, 2023
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats
, 2024
Research on the Effects of the Juncus Inflexus Subsp. Inflexus Extract on Low Dose Thioacetamide‐Induced Liver Damage: A Novel Antioxidant
, 2024
Effect of thymoquinone on NRF2/NF-kB/MAPK pathway in methotrexate-induced rat testis injury
, 2024
Effect of propolis supplementation on cadmium toxicity associated with renal and hepatic dysfunction in rats
, 2025
The Research on Endoplasmic Reticulum Stress-mediated Protective Effect of Melatonin against Cardiotoxicity Following Cisplatin Treatment
, 2024
Unveiling the Protective Potential of Crocin in Septic Acute Liver Injury via Assessment of TLR4/HGM1/NF‐κB Signaling Pathway, Oxidative Stress and Heat Shock Response
, 2025
Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer
, 2025
Protective Mechanisms of EGCG in Mitigating Oxidative Stress and Liver Toxicity From Cigarette Smoke‐Induced Damage
, 2025
Vitamin B12 Regulates the Expression of Methotrexate-Induced Increased Markers of Autophagy: An Immunohistochemical Study
, 2021
Investigation of the Therapeutic Effects of Chloroquine in Adriamycin-Induced Hepatotoxicity
, 2021
Vitamin B12 suppresses GADD153, prevents apoptosis and regulates the testicular function in methotrexate treated rat testis
, 2021
Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus due to doxorubicin
, 2021
Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study.
, 2022
Vitamin B12 Alleviates Methotrexate-Induced Lung Injury In Rat: A Histopathological, Immunohistochemical, and Biochemical Study.
, 2022
Histopathological Changes In Lung Tissue Caused By Diabetes: A Review
, 2023
Lipopolisakkarit’in neden olduğu bağırsak toksisitesine karşı biyosentetik gümüş nanopartiküllerin etkisi
, 2020
Crocin Suppresses Inflammatory Response in LPS-Induced Acute Lung Injury (ALI) Via Regulation of HMGB1/TLR4 Inflammation Pathway
, 2024
Thymoquinone attenuates doxorubicin-cardiotoxicity in rats
, 2021
Comparison of the Acute and Cumulative Dose Administrations in Doxorubicin-induced Hepatotoxicity
via Evaluation of the Histopathological Changes and Inflammation in Rats
, 2020
GÜMÜŞ NANOPARTİKÜLLERİNİN ÜZÜM ÇEKİRDEĞİ EKSTRAKTININ ENDOTOKSİK KALP DOKUSUNDAKİ HİSTOLOJİK DEĞİŞİKLERE VE TNF-ɑ VE BNP EKSPRESYONUNA ETKİSİ
, 2019
L-carnitine effects in CCl4-nephrotoxicity: Immunohistochemical evaluation of glomerular nephrin and HIF-1alpha expressions
, 2020
Effects of Melatonin Against Thioacetamide-Induced Testicular Toxicity in Rats
, 2020
Chloroquine inhibits adriamycin-induced cardiotoxicity in rats by inhibiting endoplasmic reticulum stress and inflammation
, 2020
Histological Examination of Rat Heart Tissue withChronic Diabetes
, 2020
Thymoquinone is a protective agent that reduces the negative effects of doxorubicin in rat testis
, 2020
Apilarnilin'in erkek sıçanlarda Lipopolisakkarite (LPS) bağlı testis toksisitesine karşı koruyucu rolünün belirlenmesi
, 2019
The effect of chloroquine on the TRPC1, TRPC6, and CaSR in the pulmonary artery smooth muscle cells in hypoxia-induced experimental pulmonary artery hypertension
, 2021
L-Carnitine ameliorates the liver by regulating alpha-SMA, iNOS, HSP90, HIF-1alpha, and RIP1 expressions of CCL4-toxic rats
, 2021
The Effects of Rapamycin and 3-Methyladenine on Nitric Oxide Synthase Enzymes in Cisplatin-Induced Neurotoxicity
, 2021
Chloroquine Ameliorates Adriamycin-Induced Testicular Damage by Suppressing the Inflammation and Apoptosis in Rats: A Histological, Immunohistochemical and Biochemical Study
, 2021
Reports
Kadmiyum Uyarılı Testis Hasarına Karşı Timokinonun Etkisi - AKİN ALİ TUĞRUL,KAYMAK EMİN,CEYLAN TAYFUN,Varinli Şaban
Karbon Tetraklorür İle Oluşturulan Testis Hasarında Isı Şok Protein Yoğunlukları Üzerine Karnozinin Etkisi - KARABULUT DERYA, KULOĞLU NURHAN, KAYMAK EMİN, ÖZTÜRK EMEL, ÜNSAL MURAT, AKİN ALİ TUĞRUL, YAKAN BİRKAN
Crocin Suppresses Inflammatory Response in LPS-Induced Acute Lung Injury (ALI) Via Regulation of HMGB1/TLR4 Inflammation Pathway - AKİN ALİ TUĞRUL, CEYLAN TAYFUN, KAYMAK EMİN
Sivas Çat Ormanları'nın Oribatid Akar Faunası (Acari, Oribatida) - TOLUK AYŞE, AKİN ALİ TUĞRUL
Türkiye akar faunası için yeni bir kayıt Eremobelba geographica Berlese 1908 Acari Oribatida - TOLUK AYŞE,AYYILDIZ NUSRET,AKİN ALİ TUĞRUL,Handan Ezgi Akin
ANTI-INFLAMMATORY EFFECTS OF CROCIN IN LPS-INDUCED BOWEL DAMAGE VIA SUPPRESSION OF TLR4 EXPRESSION - AKİN ALİ TUĞRUL
EFFECT OF THYMOQUINONE ON METHOTREXATE-INDUCED RAT TESTICULAR INJURY - KAYMAK EMİN, CEYLAN TAYFUN, AKİN ALİ TUĞRUL
Investigation of the effect of grape seed, silver nitrate and silver nanoparticle on kidney damage induced by lipopolysaccharide (LPS) - DOĞANYİĞİT ZÜLEYHA,KAYMAK EMİN,OKAN ASLI,AKİN ALİ TUĞRUL,ÖZTÜRK KÜP FATMA
Effects of Grayanatoxin (GTX III) on BNP Expression in Rat Heart Tissue - DOĞANYİĞİT ZÜLEYHA,KAYMAK EMİN,AKİN ALİ TUĞRUL
Effect of chloroquine in hypoxia-induced bowel damage - KAYMAK EMİN,AKİN ALİ TUĞRUL,YALÇIN BETÜL,ÖZTÜRK EMEL,CEYLAN TAYFUN,BAŞARAN KEMAL ERDEM,KARABULUT DERYA,DOĞANYİĞİT ZÜLEYHA,ÖZDAMAR SAİM,YAKAN BİRKAN
Kronik Hipoksiye Maruz Bırakılan Ratlardaki Mide Ghrelin Miktarı Uzerine Klorokuin’in Etkisi - KAYMAK EMİN,AKİN ALİ TUĞRUL,ÖZTÜRK EMEL,YALÇIN BETÜL,CEYLAN TAYFUN,BAŞARAN KEMAL ERDEM,DOĞANYİĞİT ZÜLEYHA,KARABULUT DERYA,ÖZDAMAR SAİM,YAKAN BİRKAN
Role of Inflammation in Acute and Chronic Adriamycin-induced Nephropathy - KAYMAK EMİN,AKİN ALİ TUĞRUL,DOĞANYİĞİT ZÜLEYHA,KARABULUT DERYA,TOLUK AYŞE
The Dose-dependent Effects of Doxorubicin in Rat Liver Tissue - AKİN ALİ TUĞRUL,KAYMAK EMİN,KARABULUT DERYA,DOĞANYİĞİT ZÜLEYHA,CEYLAN TAYFUN,TOLUK AYŞE,ÖZDAMAR SAİM
The Effects of Doxorubicin Administered Acute and Cronic Doses On Heart Tissue in Rats - AKİN ALİ TUĞRUL,KAYMAK EMİN,DOĞANYİĞİT ZÜLEYHA,KARABULUT DERYA,TOLUK AYŞE
Books
Research & Reviews in Health Sciences - I – Gece Kitaplığı Yayınevi