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  2. Faculty of Medicine
Academic Member

Prof. Yildiz İyidoğan

Temel Tıp
Prof. Dr. Yıldız Öner-İyidoğan graduated from the Department of Chemistry, Faculty of Science and Letters at Istanbul Technical University in 1991. She completed her Master’s degree in 1993 and her PhD in 1999 at the Department of Medical Biochemistry, Istanbul University Istanbul Faculty of Medicine. She was awarded the title of Associate Professor in Medical Biochemistry in 2005 and became a Full Professor in 2012. She served as the Coordinator of Graduate Education at the Department of Medical Biochemistry, Istanbul Faculty of Medicine, and supervised one medical specialty (residency) thesi...

Prof. Dr. Yıldız Öner-İyidoğan graduated from the Department of Chemistry, Faculty of Science and Letters at Istanbul Technical University in 1991. She completed her Master’s degree in 1993 and her PhD in 1999 at the Department of Medical Biochemistry, Istanbul University Istanbul Faculty of Medicine. She was awarded the title of Associate Professor in Medical Biochemistry in 2005 and became a Full Professor in 2012.

She served as the Coordinator of Graduate Education at the Department of Medical Biochemistry, Istanbul Faculty of Medicine, and supervised one medical specialty (residency) thesis and one master’s thesis. She has participated as a principal investigator and researcher in a total of 15 Scientific Research Projects (BAP) and is currently involved as a researcher in 3 ongoing BAP projects and 1 TÜBİTAK 1002 project.

Prof. Dr. Öner-İyidoğan has authored 37 international publications and 4 national publications. She has presented 20 papers at international congresses and 33 at national congresses. Her total citation count is 1,119, and her h-index is 21. She has also contributed as a chapter author to the book Medical Biochemistry (Editor: Prof. Dr. Figen Gürdöl), published by Nobel Publishing.

After retiring from Istanbul University in 2020, she was appointed as a founding faculty member with the rank of Professor at the Department of Medical Biochemistry, Faculty of Medicine, Istanbul Arel University. At Arel Faculty of Medicine, she served on various committees and held administrative positions as the Head of the Department of Medical Biochemistry and Dean of the Faculty of Health Sciences. She also delivered theoretical and practical Medical Biochemistry courses for Grade I and Grade II medical students.

She is currently teaching Medical Biochemistry courses in Grade I and Grade II at Istinye University Faculty of Medicine and serves as the Dean of the Faculty of Health Sciences at Istinye University.

Articles

  • Chymase and Fetuin-A in Metabolic Inflammation: Molecular Pathways Linking to Insulin Resistance , 2026
  • Fetuin-A-to-adiponectin ratio, progranulin, and CTRP-3 in overweight individuals: links to adipose tissue inflammation , 2026
  • Fetuin-A-to-adiponectin ratio, progranulin, and CTRP-3 in overweight individuals: links to adipose tissue inflammation , 2025
  • Association of Different Doses of Curcumin with Preadipocyte to Adipocyte Differentiation , 2025
  • Urinary nerve growth factor in children with overactive bladder A promising noninvasive and objective biomarker , 2013
  • Interaction of fetuin-A with obesity related insulin resistance and diabetes mellitus , 2024
  • Capsaicin Modulates Adipocyte Cell Differentiation and Inflammatory Gene Expression , 2024
  • Serum Chymase Levels in Obese Individuals: The Relationship with Inflammation and Hypertension , 2020
  • Effect Of Dietary Curcumin On Oxidant-Antioxidant Status In Testis Tissues Of Rats Fed A High-Fat Diet , 2020
  • Dietary Curcumin and Capsaicin: Relationship with Hepatic Oxidative Stress and Apoptosis in Rats Fed A High Fat Diet
  • Effect of Dietary Curcumin and Capsaicin on Testicular and Hepatic Oxidant-Antioxidant Status in Rats Fed a High-Fat Diet , 2019
  • The effect of dietary curcumin on hepatic chymase activity and serum fetuin-A levels in rats fed on a high-fat diet , 2017
  • Acute Phase Reactants in Allergic Airway Disease , 2004
  • Indices of Oxidative Stress in Eutopic and Ectopic Endometrium of Women with Endometriosis , 2004
  • The Effects of Acute Melatonin and Ethanol Treatment on Antioxidant Enzyme Activities in Rat Testes , 2001
  • Circulating ghrelin levels in obese women a possible association with hypertension , 2007
  • Early and late effects of hyperbaric oxygen treatment on oxidative stress parameters in diabetic patients , 2008
  • Dimethylarginines and inflammation markers in patients with chronic kidney disease undergoing dialysis , 2009
  • Collagen synthesis nitric oxide and asymmetric dimethylarginine in diabetic subjects undergoing hyperbaric oxygen therapy , 2010
  • Appetite regulating Hormones in Chronic Kidney Disease Patients J Ren Nutr 2011 21 4 316 321 , 2011
  • Serum Asymmetric Dimethylarginine and Nitric Oxide Levels in Obese Postmenopausal Women , 2014
  • Effect of curcumin on hepatic heme oxygenase 1 expression in high fat diet fed rats is there a triangular relationship , 2014
  • THE EFFECT OF DIETARY CURCUMIN AND CAPSAICIN ON HEPATIC FETUIN A EXPRESSION AND FAT ACCUMULATION IN RATS FED ON A HIGH FAT DIET , 2016
  • Serum fetuin A and arginase 1 in human obesity model Is there any interaction between inflammatory status and arginine metabolism , 2015
  • Changes in enzymatic antioxidant defense system in blood and endometrial tissues of women after menopause , 1997
  • Cystatin C and creatinine as indices of glomerular filtration rate in the immediate follow up of renal transplant patients , 2005
  • Curcumin prevents liver fat accumulation and serum fetuin A increase in rats fed a high fat diet , 2013
  • Advanced oxidation protein products in obese women its relation to insulin resistance and resistin , 2007
  • Prolidase I activity in liver tissue effects of ethanol and selenium , 1995
  • Evaluation of Leukocyte Arylsulphatase A Serum Interleukin 6 and Urinary Heparan Sulphate Following Tamoxifen Therapy in Breast Cancer , 2005
  • The effects of fluorides and or trace elements on the solubilities of enamel and cementum , 1996
  • The effect of melatonin administration on ethanol induced lipid peroxidation in rats , 1998
  • Evaluation of the effect of low dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics , 1999
  • Serum prolidase I activity and some bone metabolic markers in patients with breast cancer in relation to menopausal status , 2003
  • Urine 8 isoprostane F2 concentrations in patients with neurogenic bladder due to spinal cord injury , 2004
  • Determination of diagnostic and prognostic values of urinary interleukin 8 tumor necrosis factor and leukocyte arylsulfatase A activity in patients with bladder cancer , 2004
  • The relation between serum MDA and cystatin C levels in chronic spinal cord injury patients , 2005
  • Coadministration of melatonin and estradiol in rats Effects on oxidant status , 2001
  • Acute effects of estradiol and diethylstilbestrol Pro or antioxidant potential , 1999
  • Urinary nerve growth factor in children with overactive bladder a promising noninvasive and objective biomarker , 2013
  • Seminal Plazma Superoksid Dismutaz ve Total Antioksidan Düzeylerinin Erkek İnfertilitesine Etkileri , 2003
  • Appetite regulating Hormones in Chronic Kidney Disease Patients 2011 21 4 316 321 , 2011
  • Grelinin Yapısı ve Organizmadaki Fonksiyonları , 2007
  • Serum Prolidaz I aktivitesinin Kemik Yapım Yıkım İndeksi Olarak Değerlendirilmesi , 1999

Reports

  • Post-Covid Dönemde İnflamatuvar ve Oksidatif Süreçleri Etkileyebilecek Göstergeler: Kimaz ve ACE2 - MUTLU TUBA,ATAHAN ERSAN,ÇALIŞKANER ÖZTÜRK BUKET,DEĞİRMENCİOĞLU SEVGİN,ÇINAR ŞİRİN NUR,İYİDOĞAN YILDIZ
  • Kurkumin ve Kapsaisin Uygulamasının Yüksek Yağlı Diyetle Beslenen Sıçanlarda Karaciğer İleri Oksidasyon Ürünlerine Etkisi - SEYİTHANOĞLU MUHAMMED,TANRIKULU KÜÇÜK SEVDA,Küçükgergin Canan,KOÇAK HİKMET,İYİDOĞAN YILDIZ
  • The Effects of Dietary Curcumin and Capsaicin on Preventing High Fat Diet Induced Fatty Liver from Apoptosis in a Rat Model - İYİDOĞAN YILDIZ,TANRIKULU KÜÇÜK SEVDA,Küçükgergin Canan,SÖĞÜT İBRAHİM,ABBASOĞLU SEMRA,SEYİTHANOĞLU MUHAMMED,KOÇAK HİKMET
  • The Effects of Curcumin and Capsaicin on Liver DNA Fragmentation and Total Antioxidant Status in a High-Fat-Diet Model - KOÇAK HİKMET,SÖĞÜT İBRAHİM,TANRIKULU KÜÇÜK SEVDA,SEYİTHANOĞLU MUHAMMED,TUNÇDEMİR MATEM,İYİDOĞAN YILDIZ
  • Effects of Curcumin on Oxidant-Antioxidant System in High Fat Diet Fed Rats - TANRIKULU KÜÇÜK SEVDA,Küçükgergin Canan,ABBASOĞLU SEMRA,KOÇAK HİKMET,SEYİTHANOĞLU MUHAMMED,İYİDOĞAN YILDIZ
  • The Effects of Curcumin and Capsaicin on Liver DNA Fragmentation and Total Antioxidant Status in a High-Fat-Diet Model - KOÇAK HİKMET,SÖĞÜT İBRAHİM,TANRIKULU KÜÇÜK SEVDA,SEYİTHANOĞLU MUHAMMED,TUNÇDEMİR MATEM,İYİDOĞAN YILDIZ
  • YÜKSEK YAĞLI DİYETLE BESLENEN SIÇANLARDA KURKUMİNİN OKSİDAN ANTİOKSİDAN SİSTEM ÜZERİNE ETKİLERİ - TANRIKULU KÜÇÜK SEVDA,Küçükgergin Canan,ABBASOĞLU SEMRA,KOÇAK HİKMET,Seyithanoğlu Muhammed,İYİDOĞAN YILDIZ
  • The Effect of Curcumin and Capsaicin Supplementation on Fetuin A Expression and Hepatic Fat Accumulation in High Fat Diet Fed Rats - İYİDOĞAN YILDIZ,Seyithanoğlu Muhammed,ABBASOĞLU SEMRA,TANRIKULU KÜÇÜK SEVDA,KOÇAK HİKMET,ÖZDAŞ ŞULE,TOKER BEŞARET NECLA
  • Yüksek Yağlı Diyetle Beslenen Sıçanlarda Testis Dokusunda Curcuminin Oksidan Antioksidan Sistem Üzerine Etkisi - Seyithanoğlu Muhammed,Mikailova Pervane,İYİDOĞAN YILDIZ,KOÇAK HİKMET,TANRIKULU KÜÇÜK SEVDA,ABBASOĞLU SEMRA,Aydın Fatih,TOKER BEŞARET NECLA
  • Akut miyokard infarktüsünde plazma prolidaz 1 aktivitesinin incelenmesi - Özateş Sacattin,İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,BEKPINAR SELDAĞ,YILMAZ AKAR
  • Obezitede Serum Fetuin A ve ADMA Düzeylerinin Hipertansiyon ile İlişkisi - Seyithanoğlu Muhammed,TANRIKULU KÜÇÜK SEVDA,KOÇAK HİKMET,İYİDOĞAN YILDIZ,Kayan Tapan Tuğba
  • Curcumin Uygulamasının Yüksek Yağlı Diyetle Beslenen Sıçanlarda Karaciğer Yağlanması ve Oksidatif Stres Üzerine Etkisi - Seyithanoğlu Muhammed,İYİDOĞAN YILDIZ,KOÇAK HİKMET,TANRIKULU KÜÇÜK SEVDA
  • Yüksek Yağlı Diyetle Beslenen Farelerin Karaciğerinde Trigliserid Düzeyleri ve Oksidatif Stres Üzerine Enginar Yaprağı Ekstresinin Etkisi - Seyithanoğlu Muhammed,İYİDOĞAN YILDIZ,KOÇAK HİKMET,TOKER BEŞARET NECLA,UYSAL MEHMET MÜJDAT
  • Deneysel Obezite Modelinde Oral Curcumin Uygulamasının Karaciğer Trigliserid Düzeyleri ve Oksidatif Stres Üzerine Etkisi - Seyithanoğlu Muhammed,İYİDOĞAN YILDIZ,KOÇAK HİKMET,TOKER BEŞARET NECLA,UYSAL MEHMET MÜJDAT
  • İdrar NGF Düzeyleri Aşırı Aktif Mesanesi Olan Çocuk Hastalarda Tanı ve Tedavi Sürecinde Gelecek Vaat Eden Noninvaziv Bir Biomarker Olabilir mi - Seyithanoğlu Muhammed,KOÇAK HİKMET,İYİDOĞAN YILDIZ,OKTAR TAYFUN MEVLÜT,Erdem Selçuk,KOÇAK TANER
  • Miyokard İnfaktüsünde Sol Ventrikül Fonksiyon Göstergesi Olarak Arginaz I ve Fetuin A - İYİDOĞAN YILDIZ,BEKPINAR SELDAĞ,GÜRDÖL FİGEN MELEK,Ünlüçerçi Yeşim,Develi İş Seval,YILMAZ AKAR
  • Diyabetik obezlerde AOPP düzeylerinin insulin direnci ve proinflamatuvar sitokinlerle bağıntısı - İYİDOĞAN YILDIZ,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,Öner Pernur,Süzme Rafi,Esin Deniz,İŞSEVER HALİM
  • Hiperbarik oksijenin serum PINP PIIINP düzeylerine ve prolidaz aktivitesine etkisi - GÜRDÖL FİGEN MELEK,Cimşit Maide,İYİDOĞAN YILDIZ,Şengün Şermin,Yalçınkaya Seda,KOÇAK HİKMET
  • Serum grelin ve leptin düzeylerinin kan basıncı ve vucut kütle indeksi ile bağıntısı - İYİDOĞAN YILDIZ,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,Öner Pernur,Esin Deniz
  • Obezitede serum rezistin ve sitokin düzeyleri ile tip 2 diyabet ilişkisinin incelenmesi - İYİDOĞAN YILDIZ,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,Öner Pernur,Süzme Rafi,Esin Deniz
  • Spinal kord travmalı hastalarda serum malondialdehit düzeyleri ve sistatin C arasındaki ilişki - KOÇAK HİKMET,İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,KOÇAK TANER,Esin Deniz
  • Lökosit Arilsülfataz A aktiviteleri ile serum interlökin 6 ve idrar heparin sülfat düzeylerinin meme kanserli hastalarda tanısal önemi ve tedavi ile ilişkileri - İYİDOĞAN YILDIZ,Öner Pernur,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,Lama Abdül,BEKPINAR SELDAĞ,Unur Nurettin,Özbek Kır Zeynep
  • Nörojen mesaneli hastalarda 8 epi PGF2 düzeylerinin prognostik değeri ve antioksidan statüsle ilişkisi - İYİDOĞAN YILDIZ,KOÇAK HİKMET,KOÇAK TANER,GÜRDÖL FİGEN MELEK,EROL BÜLENT
  • Seminal plazma superoksid dismutaz ve total antioksidan düzeylerinin erkek infertilesine etkileri - İYİDOĞAN YILDIZ,GENÇ NİLGÜN SEMA,KOÇAK HİKMET,AKKUŞ KADİR EMRE
  • Renal transplantansyon takibinde sistatin C nin güvenilirliği ve olası graft disfonksiyonun tespitinde CRP ve SAA nın rolü - KOÇAK HİKMET,İYİDOĞAN YILDIZ,KOÇAK TANER,NANE İSMET
  • Endometriosisli olguların ötopik ve ektopik endometrium dokusunda oksidatif hasar göstergeleri - İYİDOĞAN YILDIZ,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,Korkmaz Düzgün,BUYRU HASAN FARUK
  • Melatoninin beyin antioksidan enzim aktivitelerine etkisi ve etanolle etkileşimi - İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,Öner Pernur
  • Meme kanserinde kemiğe metastaz durumunun belirlenmesinde bazı osteoblastik osteoklastik biyokimyasal göstergelerin ve serum prolidaz aktivitesinin tanısal değeri - Özbek Kır Zeynep,İYİDOĞAN YILDIZ,Öner Pernur,Özbilen Küçücük Seden,Koşer Murat
  • Menopozda hormon replasman tedavisinin kemik metabolizması ve oksidatif stres üzerine etkisi - GÜRDÖL FİGEN MELEK,Gökkuşu Cahide,ADEMOĞLU EVİN,İYİDOĞAN YILDIZ,Tata Gülten
  • Doğal ve sentetik östrojenlerin antioksidan savunma enzimlerine etkisi - Süzme Rafi,GENÇ NİLGÜN SEMA,GÜRDÖL FİGEN MELEK,İYİDOĞAN YILDIZ
  • Serum prolidaz I aktivitesinin kemik yapım yıkım indeksi olarak değerlendirilmesi - İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,Öner Pernur
  • Melatoninin antioksidan etkisinin akut alkol intoksikasyonuna bağlı lipid peroksidasyonunda incelenmesi - GENÇ NİLGÜN SEMA,GÜRDÖL FİGEN MELEK,İYİDOĞAN YILDIZ,ONARAN İLHAN
  • Oral teofilin tedavisindeki kişilerde kemik homeostazisinin oeteoblastik oeteoklastik göstergeler ve serum prolidaz aktivitesi ile araştırılması - Öner Pernur,Kolancı Çiğdem,İYİDOĞAN YILDIZ,BÜYÜKÖZTÜRK SUNA,GÜRDÖL FİGEN MELEK
  • Diabetli sıçanlarda konvülziyonların kan beyin bariyeri yıkımına etkisi - Öztaş Baria,KÜÇÜK MUTLU,İYİDOĞAN YILDIZ
  • Konvülziyonlarda kan beyin bariyeri yıkımlarının farklı beyin bölgelerinde spektral ölçüm değerleri - KÜÇÜK MUTLU,İYİDOĞAN YILDIZ,Öztaş Baria
  • Akut hipertansiyonda kan beyin bariyeri yıkımlarının dişi ve erkek sıçanda karşılaştırılması - KÜÇÜK MUTLU,İYİDOĞAN YILDIZ,Öztaş Baria
  • Effects of Curcumin Intake on Fatty Liver in High Fat Diet Fed Rats - TANRIKULU KÜÇÜK SEVDA,Seyithanoğlu Muhammed,İYİDOĞAN YILDIZ,KOÇAK HİKMET,ABBASOĞLU SEMRA,Aydın Fatih,TOKER BEŞARET NECLA
  • Effects of Curcumin Supplementation on Liver Metabolism in Rats Fed a High Fat Diet A Proteomic Approach - KOÇAK HİKMET,İYİDOĞAN YILDIZ,Ahmet Tarık Baykal,Seyithanoğlu Muhammed,ÇEVİK AYDIN,GÜRDÖL FİGEN MELEK,UYSAL MEHMET MÜJDAT
  • Effects of Curcumin Supplementation on Serum Fetuin A in Rats Fed a High Fat Diet Is Curcumin Useful for Treatment of Fatty Liver Disease - İYİDOĞAN YILDIZ,KOÇAK HİKMET,Seyithanoğlu Muhammed,GÜRDÖL FİGEN MELEK,GÜLÇUBUK AHMET,YILDIRIM FUNDA,ÇEVİK AYDIN,UYSAL MEHMET MÜJDAT
  • Urinary Nerve Growth Factor Levels in Children with Non neuropathic Overactive Bladder A Promising Biomarker - OKTAR TAYFUN MEVLÜT,KOÇAK TANER,KOÇAK HİKMET,İYİDOĞAN YILDIZ,Selçuk Erdem,ZİYLAN HASAN ORHAN
  • Plasma acylated ghrelin obestatin and leptin in different stages of chronic kidney disease patients - İYİDOĞAN YILDIZ,Öner Pernur,GÜRDÖL FİGEN MELEK,KOÇAK HİKMET,Çetinalp Demircan Pınar,ÇALIŞKAN YAŞAR KEREM,KOÇAK TANER,TÜRKMEN AYDIN
  • The relation of dimethylarginines with inflammation and oxidative stress markers in patients with chronic renal failure - Pernur Öner,İYİDOĞAN YILDIZ,KOÇAK HİKMET,GÜRDÖL FİGEN MELEK,BEKPINAR SELDAĞ,Ünlüçerçi Yeşim,KOÇAK TANER,Çetinalp Demircan Pınar
  • Serum ghrelin adiponectin asymmetric dimethylarginine ADMA and nitric oxide levels in postmenopausal obese women - KOÇAK HİKMET,İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,Pernur Öner,Deniz Esin
  • Changes in factors affecting healing of wounds during hyperbaric oxygen therapy Biomarkers of collagen synthesis nitric oxide and asymmetric dimethylarginine - İYİDOĞAN YILDIZ,Maide Cimşit,GÜRDÖL FİGEN MELEK,KOÇAK HİKMET,Şermin Sengün,Yalçınkaya Demirsöz Seda
  • Evaluation of the effect of low dose oral theophylline therapy on some bone turnover markers and serum prolidase I activity in mild asthmatics - İYİDOĞAN YILDIZ,Pernur Öner,GÜRDÖL FİGEN MELEK,Çiğdem Kolancı,BÜYÜKÖZTÜRK SUNA
  • Clinical evaluation of leukocyte arylsulphatase A serum interleukin 6 and urinary heparin sulphate estimations in breast cancer patients and their relationship to the tamoxifen treatment - Pernur Öner,İYİDOĞAN YILDIZ,KOÇAK HİKMET,Lama Abdül,BEKPINAR SELDAĞ,GÜRDÖL FİGEN MELEK,Nurettin Unur,Zeynep Özbek Kır
  • The role of melatonin on prooxidative damage caused by acute estradiol treatment - Rafi Süzme,GÜRDÖL FİGEN MELEK,GENÇ NİLGÜN SEMA,İYİDOĞAN YILDIZ
  • Influence of estrogen treatment on antioxidant defense system - GENÇ NİLGÜN SEMA,GÜRDÖL FİGEN MELEK,İYİDOĞAN YILDIZ,Rafi Süzme,YALÇIN ÖNAY
  • Postmenopausal changes in enzymatic antioxidant defence system in blood and endometrial tissues of women - İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,YALÇIN ÖNAY,BUYRU HASAN FARUK
  • The investigation of the effects of fluorides and or trace elements on the solubility of enamel and cementum surfaces of the same teeth - KORAY MELTEM,İYİDOĞAN YILDIZ,Mümin Soyman,GÜRDÖL FİGEN MELEK
  • Liver Prolidase Activity in Rats Following Chronic Alcohol Administration and Effect of Selenium - İYİDOĞAN YILDIZ,GÜRDÖL FİGEN MELEK,Yeşim Tuğrul,BEKPINAR SELDAĞ

Books

  • Tıbbi Biyokimya – Nobel Tıp Kitabevi
  • Tıbbi Biyokimya – Nobel Tıp Kitabevi
  • Tıbbi Biyokimya – Nobel Tıp Kitabevleri
  • Tıbbi Biyokimya – Nobel Tıp Kitabevi
  • Tıbbi Laboratuvar El Kitabı – İstanbul Üniversitesi Yayını
  • Tıbbi Biyokimya – Nobel Tıp Kitabevi

Awards

  • En iyi poster sunum ödülü – 2014
Prof. Yildiz İyidoğan - İstinye Üniversitesi
yildiz.iyidogan@istinye.edu.tr

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