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Academic Member

Prof. Engin Ulukaya

Temel Tıp
Professor Dr. Engin Ulukaya, after graduating from Istanbul University Cerrahpaşa Medical Faculty in 1987, completed his Medical Biochemistry specialization at Uludağ University. He completed his doctorate (PhD) at the University of Leeds (UK), School of Biochemistry and Molecular Biology. He is working on basic cancer research, cell death, cancer drug development, and personal oncology. In addition to being the chair of the Molecular Cancer Research Association (MOKAD), he is a member of the Council in EACR (European Association for Cancer Research) and a full member of the EORTC PathoBiology...
Professor Dr. Engin Ulukaya, after graduating from Istanbul University Cerrahpaşa Medical Faculty in 1987, completed his Medical Biochemistry specialization at Uludağ University. He completed his doctorate (PhD) at the University of Leeds (UK), School of Biochemistry and Molecular Biology. He is working on basic cancer research, cell death, cancer drug development, and personal oncology. In addition to being the chair of the Molecular Cancer Research Association (MOKAD), he is a member of the Council in EACR (European Association for Cancer Research) and a full member of the EORTC PathoBiology subgroup. He has published about 200 articles in international journals (Google scholar H index: 48, number of citations: 7020, April 2025). He received the “promising laboratory physician” award at the world pathology and laboratory medicine association (WASPALM) congress held in South Korea in 2003 and was awarded the WASPALM medal. He also has 32 awards in various categories, 3 of which are abroad. He is the Dean of Health Sciences at Istinye University. He is also the Director of the Molecular Cancer Application and Research Center (ISUMKAM) of the same university.

Articles

  • Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines ,2017
  • A trans-platinum(II) complex induces apoptosis in cancer stem cells of breast cancer ,2017
  • The MTT viability assay yields strikingly false-positive viabilities although the cells are killed by some plant extracts ,2017
  • Total Phenolic Content, Antioxidant and Cyto-/Genotoxic Activities of Pelargonium Quercetorum Agnew in Human Breast Cancer Cells ,2017
  • A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer ,2018

Reports

  • The Plant-Derived Triterpenoid Pristimerin is a Potent Anticancer Agent Due to Its Cytotoxic Activity on Breast Cancer in vitro and in vivo - CEVATEMRE BUSE,Erkısa Merve,AZTOPAL NAZLIHAN,KARAKAŞ DİDEM,Pınar Alper,Tsimplouli Chrisiida,Sereti Evangelia,Dimas Konstantinos,Armutak Elif I Ikitimur,Gurevin Ebru Gurel,Uvez Ayça,Mori Mattia,Berardozzi Simone,Ingallina Cinzia,Botta Bruno,ULUKAYA ENGİN
  • Cytotoxic/Apoptotic effects of the benzofuran-substituted chalcone derivatives in colon cancer. - Erkısa Merve,Pınar Alper,COŞKUN DEMET,ULUKAYA ENGİN,ARI FERDA
  • Özgün bir palladyum-barbitürat bileşiğinin anti-kanser ilaç adayı olarak preklinik analizi - DURMUS SELVI,UNAL OZLEM,SAVALAN ALTAY,ICSEL CEYDA,YILMAZ VEYSEL TURAN,VAN TELLINGTON OLAF,YAĞCI ACAR HAVVA,SHAHIN OZGUR,ULUKAYA ENGİN
  • Combination Therapy with Valproic Acid and Cu (II)- Barbiturate Complex Induces ROS-Mediated Apoptosis in Breast Cancer Stem Cell - ERKISA MERVE, AZTOPAL NAZLIHAN, ERTÜRK ELİF, ULUKAYA ENGİN, ARI FERDA
  • Paklitaksel Tedavisinin Meme Kanseri Kanser Kök Hücrelerinde miRNA Ekspresyon Profiline Etkisi - ERTÜRK ELİF, AKGÜN OĞUZHAN, ERKISA MERVE, AZTOPAL NAZLIHAN, ULUKAYA ENGİN, ZEYBEK ŞAKİR ÜMİT, KÜÇÜKALİ CEM İSMAİL, ARI FERDA

Books

  • Moleküler Kanser Biyolojisi – Kısayol
Prof. Engin Ulukaya - İstinye Üniversitesi
eulukayaistinye.edu.tr
SW

Research Areas

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